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Schuster, I. S., Andoniou, C. E., & Degli-Esposti, M. A. (2024). Tissue-resident memory NK cells: Homing in on local effectors and regulators. Immunological Reviews, 323(1), 54–60. Added by: Dr. Enrique Feoli (14/12/2025, 16:10) Last edited by: Dr. Enrique Feoli (14/12/2025, 17:12) |
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| Resource type: Journal Article Published DOI: 10.1111/imr.13332 ID no. (ISBN etc.): 1600-065X BibTeX citation key: Schuster2024 View all bibliographic details  |
Categories: BioAcyl Corp, Innate immunity Subcategories: NKCs Keywords: immune-regulation, inflammation, memory, natural killer cells, tissue-residency, viral infection Creators: Andoniou, Degli-Esposti, Schuster Collection: Immunological Reviews |
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| Abstract |
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Natural killer (NK) cells are the prototype innate effector lymphocyte population that plays an important role in controlling viral infections and tumors. Studies demonstrating that NK cells form long-lived memory populations, akin to those generated by adaptive immune cells, prompted a revaluation of the potential functions of NK cells. Recent data demonstrating that NK cells are recruited from the circulation into tissues where they form long-lived memory-like populations further emphasize that NK cells have properties that mirror those of adaptive immune cells. NK cells that localize in non-lymphoid tissues are heterogeneous, and there is a growing appreciation that immune responses occurring within tissues are subject to tissue-specific regulation. Here we discuss both the immune effector and immunoregulatory functions of NK cells, with a particular emphasis on the role of NK cells within non-lymphoid tissues and how the tissue microenvironment shapes NK cell-dependent outcomes.
Added by: Dr. Enrique Feoli Last edited by: Dr. Enrique Feoli |
| Notes |
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\_eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1111/imr.13332
Added by: Dr. Enrique Feoli Last edited by: Dr. Enrique Feoli |