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Cheol Woo, Y. (2004). Changes in Tissue pH and Temperature after Incision Indicate Acidosis May Contribute to Postoperative Pain. Anesthesiology. 
Added by: Dr. Enrique Feoli (05/08/2022, 18:02)   Last edited by: Dr. Enrique Feoli (05/08/2022, 18:10)
Resource type: Journal Article
BibTeX citation key: CheolWoo2004
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 Categories: BioAcyl Corp
Subcategories: Wound Healing
Creators: Cheol Woo
Collection: Anesthesiology		 Views: 3/250
Abstract
A decrease in pH occurs immediately after incision and is sustained for at least 4 days. During the period of decreased tissue pH, pain behaviors are evident. When the tissue pH returns to normal, pain behaviors are diminished. The decreased pH is localized at the incision site and not to areas surrounding the incision. Decreased pH likely contributes to nociceptor sensitization and pain related behaviors after incision. The magnitude of the pH change varies among tissues. An increase in hind paw skin temperature does not play a role in these pain-related behaviors.
Added by: Dr. Enrique Feoli  
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