BioAcyl Corp |
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| Resource type: Journal Article BibTeX citation key: CheolWoo2004 View all bibliographic details |
Categories: BioAcyl Corp Subcategories: Wound Healing Creators: Cheol Woo Collection: Anesthesiology |
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| Abstract |
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A decrease in pH occurs immediately after incision and is sustained for at least 4 days. During the period of decreased tissue pH, pain behaviors are evident. When the tissue pH returns to normal, pain behaviors are diminished. The decreased pH is localized at the incision site and not to areas surrounding the incision. Decreased pH likely contributes to nociceptor sensitization and pain related behaviors after incision. The magnitude of the pH change varies among tissues. An increase in hind paw skin temperature does not play a role in these pain-related behaviors.
Added by: Dr. Enrique Feoli |