BioAcyl Corp
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Verdolino, D. V., Thomason, H. A., & Fotticchia, A. (2021). Wound dressings: curbing inflammation in chronic wound healing. Emerging Topics in Life Sciences, 5(4), 523–537. Added by: Dr. Enrique Feoli (02/09/2022, 11:01) Last edited by: Dr. Enrique Feoli (02/09/2022, 11:02) |
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| Resource type: Journal Article DOI: 10.1042/etls20200346 ID no. (ISBN etc.): 2397-8554 BibTeX citation key: Verdolino2021 View all bibliographic details  |
Categories: BioAcyl Corp Subcategories: Wound Healing Creators: Fotticchia, Thomason, Verdolino Collection: Emerging Topics in Life Sciences |
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| Abstract |
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{Chronic wounds represent an economic burden to healthcare systems worldwide and a societal burden to patients, deeply impacting their quality of life. The incidence of recalcitrant wounds has been steadily increasing since the population more susceptible, the elderly and diabetic, are rapidly growing. Chronic wounds are characterised by a delayed wound healing process that takes longer to heal under standard of care than acute (i.e. healthy) wounds. Two of the most common problems associated with chronic wounds are inflammation and infection, with the latter usually exacerbating the former. With this in mind, researchers and wound care companies have developed and marketed a wide variety of wound dressings presenting different compositions but all aimed at promoting healing. This makes it harder for physicians to choose the correct therapy, especially given a lack of public quantitative data to support the manufacturers’ claims. This review aims at giving a brief introduction to the clinical need for chronic wound dressings, focusing on inflammation and evaluating how bio-derived and synthetic dressings may control excess inflammation and promote healing.}
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